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White House Launches TrumpRx Discounted Drug Website

On February 5th, President Donald Trump announced the launch of TrumpRx.gov, a federally operated website to help individuals buy prescription medications at discounted cash prices. The website boasts savings for popular GLP-1s, including the Wegovy pill and injection, Ozempic and Zepbound. Medications for asthma and infertility are also available. At this time, the website does not sell or dispense drugs. Instead, TrumpRx.gov currently offers coupons for drug discounts. Patients can access the drugs through the instructions shown for each individual drug offer.

 

Through TrumpRx.gov, patients will be able to access discounts on 43 of the most popular and highest-priced medicines in the country, paying prices in line with the lowest paid by other developed nations (known as the most-favored-nation [MFN] price).

 

This launch features drugs from the first five manufacturers to reach MFN pricing agreements with the Trump administration, including AstraZeneca, Eli Lilly, EMD Serono, Novo Nordisk and Pfizer. Additional drugs from 11 other companies that have signed MFN pricing deals will be made available through TrumpRx.gov in the coming months. The discounts range from 33% off Pfizer’s Xeljanz (which treats ulcerative colitis) to 93% off Cetrotide (used in fertility treatments).

How to Use TrumpRx.gov

These website deals would be “only available for cash-paying patients.” The discounts are not available to patients who are paying through their health insurance and do not apply to insurance deductibles. Discounted drugs can be obtained at participating pharmacies using coupon codes displayed on the website or directly on manufacturers’ websites.
 
The website explains that patients will click a button stating they aren’t enrolled in a government insurance program, such as Medicare, and that they won’t seek insurance reimbursement for out-of-pocket costs or count them toward a deductible. Then, they can get a coupon to take to a participating pharmacy for a discount. Some offers may require consumers to go to the company’s website instead.

Understanding the TrumpRx Discounted Drug Website

TrumpRx is a newly launched federal website intended to help Americans access lower prices on select prescription medications by showcasing discounted cash pay options negotiated directly with pharmaceutical manufacturers. The site is part of a Most Favored Nation (MFN) pricing initiative that aims to align U.S. drug costs with the lowest prices paid in other developed countries.
 
Because TrumpRx works differently from traditional health insurance, it’s worth taking time to understand what the platform offers, its limitations, and when it may or may not be financially advantageous.

TrumpRx currently operates much like a prescription drug discount card program. The platform is an informational and referral website and creates custom coupons for some drugs. It does not fill prescriptions, process payments or act as a pharmacy. Instead, it displays discounted prices for a limited set of medications, currently about 40 brand-name drugs, and then directs users to third-party websites to complete their purchase. As the federal government finalizes additional MFN pricing agreements, more medications will be added, and the list of available drugs will expand over time. The website’s functionality may also develop over time.

The five steps below detail how TrumpRx works from the moment you begin using the platform and explain how it can help you access available prescription discounts:
 
  1. Search for your medication. Users can either click “Browse Medications” or type their prescription into the TrumpRx search bar to see if it’s included in the program.
  2. Review pricing and eligibility. If the medication is listed, the website displays discounted cash‑pay pricing and instructions for accessing the offer.
  3. Follow the purchase instructions. TrumpRx directs users either to a manufacturer’s online ordering site or to a downloadable coupon for use at participating pharmacies.
  4. Secure a valid prescription. A prescription from a health care provider is still required. Some medications may need to be filled through specific specialty pharmacies.
  5. Complete the purchase outside of insurance. All TrumpRx purchases are cash‑pay only. They do not apply to deductibles, out‑of‑pocket maximums, or insurance tracking.
It’s important to note that many prices listed on TrumpRx do not require the TrumpRx coupon. For example, some medications, such as the Wegovy pill, are already available at the same cash pay price directly through manufacturers or pharmacies. The prices shown on TrumpRx reflect the government-negotiated MFN pricing. Because MFN pricing is a standardized price floor, it may match or closely resemble prices that consumers can already obtain elsewhere without using a TrumpRx coupon.
TrumpRx can provide meaningful savings, but the value depends on the individual’s insurance coverage and prescription needs. For many people with insurance, their standard copay may still be lower than a cash pay price. However, certain groups may find the platform particularly helpful.
 
The following people may benefit from using TrumpRx:
 
  • Uninsured individuals—TrumpRx offers access to discounts without requiring coverage.
  • Members of high deductible health plans—Those who haven’t met their deductible and may be unlikely to do so may find cash pay pricing more affordable for specific medications.
  • People prescribed medications with limited or no insurance coverage—Some specialty drugs are expensive or excluded from certain plans; TrumpRx may offer a lower out-of-pocket price.
  • Individuals seeking specialty treatments that most insurance plans do not cover—Several specialty medications fall outside traditional pharmacy benefits entirely. For example, Gonal F, a commonly prescribed fertility medication, is frequently excluded from insurance plans. Cash-pay programs like TrumpRx may therefore offer a more affordable price for some patients paying entirely out of pocket.
Eligibility for TrumpRx depends on whether a user is simply viewing cash pay prices or attempting to use a manufacturer-sponsored coupon. While the general website is open to everyone, certain high value offers, such as those for glucagon-like peptide-1 (GLP 1) medications, have stricter requirements.
 
The following users are eligible to view prices and follow purchase links for all medications:
 
  • Anyone, regardless of age
  • Residents of any location
  • People with commercial insurance, government insurance or no insurance
  • Users who want to compare prices or purchase medications at the listed cash pay rates
For some medications, the website requires users to meet the following requirements:
 
  • Be 18 years of age or older
  • Live in the United States or a U.S. territory (Puerto Rico, Guam, U.S. Virgin Islands, Northern Mariana Islands, American Samoa)
  • NOT be enrolled in any government-funded medical or prescription program, such as:
    • Medicare
    • Medicaid
    • Medigap
    • TRICARE
    • Veteran Affairs (VA) or Department of Defense programs
    • Any state or federal assistance program
  • Not have both commercial and government coverage (any government coverage makes the user ineligible)
  • Agree not to seek insurance reimbursement for purchases made with the coupon
  • Agree not to apply coupon based purchases toward deductibles or out of pocket maximums.
TrumpRx currently offers discounted pricing on more than 40 high-cost, brand-name medications, including several well known treatments for chronic conditions, fertility support and weight management. The list will continue to expand as additional manufacturers finalize MFN pricing agreements.
 
One of the most notable examples is Wegovy, a widely used GLP 1 medication for weight management. Under the MFN pricing, Wegovy becomes significantly more affordable than typical U.S. list prices, with potential savings of $1,000 or more per month, depending on the formulation and dosage. These substantial price reductions represent some of the steepest discounts currently available on the platform and demonstrate the level of savings that may become more common as additional drugs are added over time.
 
The following are some of the featured TrumpRx medications and their estimated savings, as listed on the website launch:
 
  • Wegovy (oral pill)—Used for chronic weight management in adults with obesity or overweight.
    • TrumpRx price: $149/month
    • Original price: $1,349/month
  • Ozempic (semaglutide)—Used for Type 2 diabetes management and cardiovascular risk reduction.
    • TrumpRx price: $199-$350/month
    • Original price: $1,028/month
  • Zepbound (tirzepatide)—Used for weight management; also used in some patients with Type 2 diabetes.
    • TrumpRx price: $299-$449/month
    • Original price: $1,087/month
  • Gonal F—Used for ovarian stimulation in fertility treatments, such as in vitro fertilization (IVF).
    • TrumpRx price: $168 per pen
    • Original price: $966-$1,449 per pen
  • Cetrotide (cetrorelix)—Used for preventing premature ovulation during IVF cycles.
    • TrumpRx price: $22.50
    • Original price: $316
  • Ovidrel—Used for triggering ovulation to support timed intercourse or IVF.
    • TrumpRx price: $84
    • Original price: $251
  • Xeljanz—Used for rheumatoid arthritis, psoriatic arthritis and ulcerative colitis.
    • TrumpRx price: $1,518.30
    • Original price: $2,277.43
  • Eucrisa—Used for eczema (atopic dermatitis).
    • TrumpRx price: $158.48
    • Original price: $792.40
  • Zavzpret—Used for treating migraines.
    • TrumpRx price: $594.83
    • Original price: $1,189.65
  • Tikosyn—Used for treating irregular heart rhythms (atrial fibrillation and flutter).
    • TrumpRx price: $336
    • Original price: $672

For More Information

A recent KFF survey found that two-thirds of U.S. adults are worried about affording health care for themselves and their families, outranking other expenses like groceries and gas. Furthermore, a majority of Americans (56%) said they expect health care to become less affordable in the coming year. Prescription drugs are a big portion of Americans’ health care costs.
 
The vast majority of Americans have health insurance and likely won’t need to use TrumpRx. Implications of MFN are still unclear and, in some cases, a medication may be cheaper with insurance.
 
For more information about the discounted drugs, visit the TrumpRx.gov website where you can explore the FAQ section and stay updated on newly negotiated drugs as they are added to the program. The site also allows users to opt in to receive email notifications, ensuring they receive alerts whenever new medications or pricing updates become available. You may also consider speaking with your insurance provider to compare all available prescription‑pricing options and help ensure you secure the most cost‑effective coverage for your needs.
 
Individuals should continue to monitor prescription drug changes. We’ll keep you updated with any notable developments.
 
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This article is to be used for informational purposes only and is not intended to replace the advice of an insurance professional. The content is of general interest and is not intended to apply to specific circumstances. It should not be regarded as legal advice and not be relied upon as such. In relation to any particular problem which they may have, readers are advised to seek specific advice. © 2026 Zywave, Inc. All rights reserved.

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Caitlin Rimmer
Caitlin is a Catawba College graduate and the Marketing Communications Coordinator at Parrott. She manages social media, website updates, client communications, and marketing materials.